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Zithromax is an unusual antibiotic in that it stays in the body for a significant period of time after the required doses. Due to the differences in the way proteins are made in bacteria and humans, the macrolide antibiotics do not influence the production of proteins in humans. The Azithromycin and prevent it from being absorbed from the intestine. If you feel better in a few days. This medicine at the same time as magnesium-based antacids because antacids will bind the Azithromycin and prevent it from being absorbed from the intestine.