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Do not take conjugated estrogens with or without food. Talk with your doctor about your individual risks before using conjugated estrogens. What is the most important information I should know about conjugated estrogens? Women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. Long-term treatment with conjugated estrogens may increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus.
